Here are some cartoons on a variety of world issues by R.C. Bowman, cartoonist for the Minneapolis Tribune in 1900.
Uncle Sam to the Senator: "Ho there! Take that bill in hand, will you? That other fellow seems to be too reckless."
There were two competing ideas on where to build a canal through Central America at this point in history. A rival to the Panama Canal route would have gone through Nicaragua from Bahia de Punta Gorda in the east, to Lake Nicaragua and out to the Pacific.
John Bull: "Heavy? Of course it's heavy. But think of the glory."
Great Britain was in the middle of the Boer War in South Africa at this time.
Looking for his Thanksgiving dinner."
The United States sent warships to occupy Izmir (Smyrna) in order to collect indemnities against Turkey (the Ottoman Empire) for "outrages committed against missionaries." Here's a New York Times article. Keep in mind, this turkey pun was a bit younger back then.
The World: "You know, uncle, it's getting so I do almost all my trading here, now!"
Uncle Sam: "I'm glad to hear it; and to be candid, I'd sooner have your trade than that of any other planet I know of."